Maine Organic Farmers and Gardeners Association


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The complex architecture and epigenomic impact of plant T-DNA insertions

January 18, 2019 – By Florian Jupe et al., PLoS ONE – We discovered that insertion of the anticipated DNA fragment occurred as multiple concatenated full and partial fragments that led in some cases to intra- and interchromosomal rearrangements. Our analysis of the epigenetic landscapes showed variable effects from silencing of the integrated foreign DNA to alterations of chromatin marks and thus chromatin structure and functionality.

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